High-Performance Thin-Layer Chromatography (HPTLC) is the method of choice for the analysis of complex and variable samples. Conventionally, manual user intervention is necessary between each step of the HPTLC workflow. With the CAMAG HPTLC PRO System, the era of full automation throughout the entire workflow begins. In this webinar, Dr. Melanie Broszat, Scientific Business Development Manager at CAMAG, demonstrates the power of this revolutionary system based on polysaccharide content of honey samples representing the field of sugar analysis by HPTLC.

The semi-automated DFC-820SP system is composed of a PTWS 820D dissolution bath with built-in individual vessel centering, full tubing installation in PTFE, the EPE-820 auto sampling system, a PT-SP8 syringe pump and a PTFC-2/8 fraction collector. For more information on the DFC-820SP visit: https://www.pharma-test.de/en/products/dissolution-testing/offline-automated-dissolution-systems/p-dfc-820sp-including-ptws-820d-dissolution-bath/ CONTENT: - 0:10 Composed of: PTWS 820D dissolution bath, PT-SP8 high precision syringe pump and PTFC-2/8 SP fraction collector - 0:23 Large color, touch screen to control the instrument - 00:37 Visual signals on the display inform the user of the status of critical instruments parameters - 00:47 For manual sampling staggered stirrer start is possible - 00:56 Optional TM-820 tablet magazine for synchronous drop of all samples - 01:14 The TM- 820 tablet magazine is supported by flexible strings to avoid any risk of blockage - 01:24 Optional EPE-820 sampling system automatically lowers and raises the sampling probes - 01:34 Attached to the EPE-820, the ITM-820 temperature monitoring system reads and reports the media temperature inside the individual vessels during sampling - 01:44 PT-SP multi–syringe pump: Designed for parallel sample withdrawal and dosage of media from a dissolution bath - 02:16 PTFC-2/8SP offers automated sampling of up to 20 cycles with 8 vials each. The collecting dish is easy to load and unload - 02:39 The magazine includes low evaporation vessel sealing covers and magnetic holders for the tube cleaning device - 02:52 DFC-820SP Offline Automated Tablet Dissolution System Alternative tablet dissolution baths with 6 stations: PTWS 120D and PTWS 120S - 03:00 PTWS 120D is a compact 6-station tablet dissolution bath - 03:14 Available in the PTWS 120S version with individual stirrer speed control for all 6 stations

HPTLC has been proven as a reliable and robust analytical method. In this webinar, Dr. Melanie Broszat presents the method for quality control of lipid-based formulations like mRNA vaccines with the fully automated HPTLC PRO System. Furthermore, she discusses the use of HPTLC coupled with Mass Spectrometry in the field of lipidomic research.

The Pharma Test PTF 200 is a double drum tablet friability and abrasion test instrument. It is manufactured in compliance to the USP 1216, EP 2.9.7 and JP 14 pharmacopoeias. The instrument features an automated sample discharge at the end of a test and the possibility to connect an analytical balance. The PTF 200 is part of the PTF series – with one to six drums. For more information on the PTF 200 visit: https://www.pharma-test.de/en/products/galenic-instruments/tablet-friability-testing/p-ptf-200/ Content: - PTF 200 Tablet Friability Test Instrument 00:07 - The PTF 200 is part of the PTF series – with one to six drums 00:10 - 100% USP, EP and JP compliant 00:17 - Option to adjust speed from 25 to 75 rpm 00:25 - Creating test methods is easy and fully guided 00:39 - Click wheel for quick menu navigation 00:45 - Dual operation mode: number of revolutions or rotation time 00:52 - Alternative tablet filling through the opening hole of the drums 01:27 - Automatic sample discharge at the end of a test 01:54 - Clear Plexiglas collectors with magnetic positioning 02:00 - Easy user management 02:15 - USB interface: Save test reports, install updates and different languages via USB flash drive 02:32 - Integrated printer optional for the PTF 200 02:41 - FURTHER OPTIONS 02:57 - 10-degree angle stand for heavier, larger or odd-shaped tablets 03:00 - Abrasion drums are also available 03:14

The DSR-M automated dissolution sampling robot is designed specifically for the sample transfer and sample processing from a 6 to 8 (DSR-M8) or a 12 to 13 (DSR-M13) vessel dissolution bath. This unique and versatile instrument allows collecting, dilution and/or processing samples over very short time intervals. It can also be used for dissolution medium replenishment to conform to USP/EP volume loss rules. For media replacement, the CAT-MRM module is used and eliminates the need for separate refilling tubing lines compared to conventional offline systems. For more information on the DSR-M visit: https://www.pharma-test.de/en/products/dissolution-testing/offline-automated-dissolution-systems/p-dsr-m-dissolution-sampling-robot/ CONTENT: - 00:16 Edit the method using the instruments keypad - 00:33 Safety switches prevent starting the instrument in case the racks are not inserted correctly - 00:44 The samples are withdrawn from the dissolution bath and collected into the vials inside the DSR-M collection rack - 01:13 The sampled volume is automatically replaced into the dissolution vessels; a dedicated pump fills the replacement media container (optional) - 01:22 The collected samples can be transferred into the second rack to perform a dilution step (optional) - 01:34 The universal racks can be converted to be used with HPLC vials instead of open vials with a few simple steps - 01:47 The individual needle can pierce cross slit closed vials - 02:10 DSR-M includes an integrated report printer - 02:21 The CAT-M piston pump module is fully integrated into the DSR-M housing - 02:28 The MFC-12 manual filter changer is used to add filtration to the sampling process (optional) - 02:35 Standard round filter suitable for HPLC analysis can be inserted and removed easily - 02:57 The collection area of the DSR-M is easily accessible to take out the racks or to clean the instrument

HPTLC Analysis – made easy visionCATS stands for ease of use and intuitive simplicity. The software organizes the workflow of HPTLC, controls the involved CAMAG instruments, and manages data. The easy to navigate user interface effectively guides the user through the chromatographic process – from definition of samples and substances to reporting of results.

The PT-TD300 is used to test the tapped (or “tamped”) density and apparent density of powders, granules, pigments and similar products in compliance with the current USP 616 methods 1 and methods 2 as well as with EP 2.9.34, DIN EN ISO 787-11 and ASTM B527. The instrument automatically calculates the tapped density, Hausner flowability ratio and Carr compressibility index after each test and documents the results via the integrated protocol printer. For more information on the PT-TD300 visit: https://www.pharma-test.de/en/products/galenic-instruments/powder-testing/p-pt-td300/ CONTENT: - 00:17 For tapped and apparent density testing of powders, granules, pigments and similar products - 00:23 100% USP and EP compliant - 00:27 Different cylinder positions for different tapping heights according to USP (= 14 mm) and EP (= 3 mm) - 00:46 Click wheel for quick menu navigation - 00:51 Creating test methods is easy and fully guided - 01:54 Integrated Printer - 02:01 USB interface: Save test reports, install updates and different languages via USB flash drive - 02:08 Easy user management

This video shows the general functionality of the HPTLC PRO Module PLATE STORAGE.