A high-performance thin layer chromatography plate can look like a simple silica plate or foil, but it behaves like a sensitive chemical surface. Change the moisture in the air around it and the same method can produce different migration distances, altered resolution or broader bands. Humidity is one of the most crucial variables in HPTLC. It affects the activity of the stationary phase, the movement of the mobile phase, and the interaction between analytes and the plate. In

About the UAM: It is central to R&D and low-volume batch manufacturing in the pharmaceutical, chemical, food, and cosmetic industries, including equipment like blenders, mixers, homogenizers, granulators, pelletizers, crushers, coating pans, and even for dosing & filling of liquid and semi-solid preparations. The intelligent design of the UAM Universal Motor Drive enables quick and efficient changeover of attachments and the connection of peripherals, such as foot pedals and

Non-de-aerated media significantly affects the outcomes of a tablet dissolution test. For instance, they can enhance the Prednisone release rate by up to 50% compared to using properly de-aerated media. In the images below, a Prednisone Test is displayed, with both images captured after 10 minutes. The left image shows de-aerated media, with no floating particles present. In contrast, the right image shows non-de-aerated media, leading to a higher release rate due to floating

Understanding the relative nucleation and growth kinetics of polymorphs is essential for controlling crystallization processes and selectively producing desired crystal forms. In the recently published paper, “Nucleation and Growth Kinetics in a Polymorphic System—The Case of Tolfenamic Acid,” the concomitant crystallization of stable Form I and metastable Form II of tolfenamic acid (TFA) from isopropanol was investigated using induction-time distributions obtained from Cryst

Authenticating botanical materials can be challenging, especially when a large numbers of samples must be evaluated or differences between chromatographic fingerprints are subtle. CAMAG's latest application note demonstrates how One-Class Support Vector Machine (OC-SVM) classification in visionCATS can be combined with HPTLC fingerprinting to support a standardised, data-driven approach to authenticity assessment, using red Asian ginseng as an example. Technical summary: Uses

We are pleased to present the new 5-in-1 tablet hardness tester, PTB 430. The PTB 430 includes a carousel that accommodates up to 20 samples and can measure up to five different parameters of a sample. Positioned between the PTB 330 and PTB 500 NICE, the PTB 430 shares the 20-sample carousel feature with the PTB 500 NICE but lacks the audit trail and additional software features like electronic signatures. Instead, the PTB 430's software is based on the PTB 330, providing a s

Chromservis has introduced Flash chromatography columns for high performance purifications. New EasyFlash columns offer high efficiency for a fast separation and isolation of impurities, reaction products and intermediates. Chromservis offer wide range from 4 g up to 1600 g, EasyFlash columns with various silicagel types – spherical and irregular.

The increasing demand for sustainable plastic waste management has heightened interest in solvent-based recycling as an alternative to traditional recycling methods. Unlike mechanical recycling, solvent-based recycling selectively dissolves target polymers, allowing for the efficient separation of contaminants, additives, and other plastics prior to polymer recovery. The success of this process relies on identifying solvents that offer high polymer solubility while adhering t

Chromservis latest pharmaceutical application note, demonstrating the analysis of Sunitinib Malate, a key targeted cancer therapy used in the treatment of RCC, GIST, and pNET. This application showcases a straightforward, robust, and dependable HPLC/LC-MS method designed with the ASTRA® C18-HE column, providing outstanding chromatographic performance for pharmaceutical quality control, method development, and bioanalytical applications. for more information contact info@chrom

In stock: p/n 034.5629 HPTLC plates silica gel 60 F254, 10 x 10 cm, pack of 100 p/n 034.5642 HPTLC plates silica gel 60 F254, 20 x 10 cm, pack of 50 For more information contact info@chromatechscientific.com

Chromservis has shared their latest Application Note (#649) focused on the detection, quantification, and impurity profiling of Lisdexamfetamine. The new method employs the ASTRA® Phenyl-Hexyl-HE column to achieve outstanding resolution and ideal separation of Lisdexamfetamine enantiomers and d-amphetamine impurities. Highlights: Target Analytes: Lisdexamfetamine dimesylate and its related impurity profile. Column Used: ASTRA® Phenyl-Hexyl-HE Method Benefits: Simple isocratic

Cleaning Validation Cleaning validation is a crucial phase in the validation process of industrial plants, ensuring that all reaction vessels in contact with products are thoroughly cleaned. This step is vital to prevent cross-contamination and maintain product quality. CAMAG's HPTLC system streamlines this validation by enabling the simultaneous analysis of multiple samples on a single plate, which improves throughput and reduces analysis time. The system's capability to man

Range of LC and GC Columns available for more information contact info@chromatechscientific.com

Chromservis has released new upcoming dimensions of ASTRA® C18-Hybrid columns. Column description Part No. Columns with 3µm particles ASTRA® C18-HYBRID HPLC column, 3,0 µm 100 mm × 3,0 mm AST-6016-II30 ASTRA® C18-HYBRID HPLC column, 3,0 µm 150 mm × 3,0 mm AST-6016-IK30 ASTRA® C18-HYBRID HPLC column, 3,0 µm 50 mm × 4,6 mm AST-6016-IG46 ASTRA® C18-HYBRID HPLC column, 3,0 µm 100 mm × 4,6 mm AST-6016-II46 ASTRA® C18-HYBRID HPLC column, 3,0 µm 150 mm × 4,6 mm AST-6016-IK46 ASTRA®

PTWS 830 is an 8-position, compact tablet dissolution testing instrument for solid dosage forms as described in USP chapter <711/724> and EP section<2.9.3/4> as well as the BP, DAB and Japanese Pharmacopeia section <15>. Integrated audit trail ensures 21 CFR Part 11 regulatory compliance Flexible user management system with unlimited number of users ensures secure access The modern user interface is easy to use and quick to learn MonoShaft™ stirring tool design avoids re-adju

The PT-LT100 leak tester is employed to assess the integrity of packed strips, blisters, and small sachets containing tablets, granules, liquids, and more. This device evaluates the quality of the packaging process and verifies that the seals around the product are completely intact. The PT-LT100 is crafted to detect the tiniest holes and flaws in blister packs and other semi-rigid product packaging. It fully adheres to the current USP <1146> monograph. Leak testing is extens

The Pharmag Pilot Plant System is designed for specialised uses such as developing new products, transitioning from testing to small-scale production, and creating specialty materials that are not typically produced in large volumes. This type of equipment is well-suited for both the fine chemical and cosmetics sectors, as well as the pharmaceutical industry. The Pharmag range is also widely used in Pharmacy teaching departments at universities and for producing low-volume, s